DHEA, short for dehydroepiandrosterone, is an important hormone produced naturally in the body by the adrenal glands. DHEA levels peak in your 20s and 30s, after which they decline with age. What does DHEA do? DHEA has several important functions:

  • It acts as a precursor to male and female sex hormones like testosterone and estrogen. This is why DHEA levels are highest when you are young and reproductive.
  • Research shows DHEA may help improve bone density, muscle strength, immunity, and heart health. It may also have anti-aging effects.
  • DHEA supplements have been used to help treat conditions influenced by hormones like adrenal insufficiency, depression, and systemic lupus erythematosus (SLE). However, evidence on these uses is inconsistent.
Are DHEA supplements safe? In the US, DHEA is available as an over-the-counter supplement. However, there are some safety concerns with taking DHEA supplements:
  • DHEA supplements may interfere with hormone-sensitive conditions like breast cancer or prostate cancer. Use caution if you have any hormone-related disorders.
  • High doses may cause side effects like acne, hair loss, facial hair growth in women, and mood changes. Stick within the standard dosage range of 25-50 mg per day.
  • DHEA quality and safety aren't well-regulated in supplements. Purchase from reputable manufacturers that adhere to good manufacturing practices (GMP).
Always talk to your doctor before taking DHEA supplements, especially if you take any medications or have an underlying health condition. Start with low doses and have your DHEA levels tested periodically to make sure they aren't getting too high. The bottom line DHEA is a hormone that declines with age but may offer anti-aging, hormonal, and other health benefits when taken as a supplement in appropriate doses. However, quality, safety, and interactions with medications and health conditions are concerns, so consult your healthcare provider before using DHEA.

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